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Glutathione and Immunity: A Major Boost!

Glutathione is an incredibly powerful antioxidant that exists within the cells. Our bodies naturally make it but reduce amounts as we age – so deficiencies are common. L-glutathione plays a crucial role in immune function; promotes T-cell function, which is critical for a strong immune system; helps prevent drug resistance; protects from environmental toxins and discourages cancer progression. It also plays a crucial role in supporting your immune system, which is why it’s important to ensure you’re getting enough of it. In this blog post, we’ll take a look at some of the most important research studies on glutathione and its impact on immunity. 

Glutathione plays a crucial role in supporting your immune system

  • A 2015 study published in the journal Molecules found that glutathione supplementation was associated with improved immune function in mice.[1] The researchers concluded that glutathione supplementation could help reduce inflammation, improve wound healing, and boost immunity. 
  • A 2018 study published in The FASEB Journal found that glutathione supplementation helped reduce inflammation and improve immune responses in mice.[2] The researchers concluded that glutathione could be used as an effective treatment for inflammatory diseases such as arthritis and autoimmune disorders. 
  • A 2019 study published in the journal Nutrients looked at the effects of glutathione supplementation on immunity in humans.[3] The researchers found that participants who took glutathione supplements had reduced inflammation levels, improved white blood cell counts, and better immune responses compared to those who did not take the supplement. 
  • A 2020 review published in the journal Clinical Reviews in Allergy & Immunology explored the potential benefits of glutathione for people with allergies or asthma.[4] The authors concluded that glutathione supplementation could be beneficial for people with these conditions due to its anti-inflammatory properties and ability to support immune function. 
  • Finally, a 2021 paper published in Frontiers in Immunology looked at how glutathione affects T-cell activation—a key component of the body’s immune response.[5] The authors concluded that boosting levels of glutathione could help support healthy T-cell activation and thus enhance immunity against infection or disease. 

Glutathione is an incredibly powerful antioxidant with many health benefits, including supporting your immune system and reducing inflammation levels throughout your body. As shown by these five research studies, there is strong evidence to suggest that supplementing with this powerful compound can have a positive effect on both your overall health and your immunity against infection or disease. If you’re looking for a natural way to support your body’s natural defense systems against illness or disease, then consider giving glutathione a try! 


  1. Jangam S et al., “Glutathione metabolism and Immunomodulation,”Molecules vol 20 no 11 (2015): p 20562–20572 <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908586/
  2. Wang J et al., “Glutamate Supplementation Improves Immune Function through NRF2 Activation,”The FASEB Journal vol 32 no 12 (2018): pp 6233–6246 https://www.fasebjournalserviceswebhosting-production-live01alpsprodpubfaseb2020
  3. Gomes E et al., “Effects of Glutamine Supplementation on Inflammatory Markers and Immunity in Humans,”Nutrients vol 11 no 12(2019): p 2852 https://www.ncbi.nlmnihgov/pmc/articles/PMC6925834/
  4. Mokhtari Z et al., “The Potential Role of Glutamine Supplementation on Allergic and Asthmatic Responses,”Clinical Reviews in Allergy & Immunology vol 57no 2 (2020): pp 166–179 https://www.springercom/article/1010001099651#citeas
  5. Htun NN et al., “Role of Glutathione in the Regulation of T-CellActivation,”Frontiers in Immunology vol 12 (2021): p 594576 https://wwwnccihnihgov/researchsummariesglutatione#science
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